Multiple malignant epithelioid mesotheliomas of the liver and greater omentum: a case report and review of the literature
© The Author(s). 2017
Received: 26 February 2017
Accepted: 3 May 2017
Published: 10 May 2017
Malignant mesothelioma commonly arises from the pleura, but can also arise from the peritoneum, pericardium, and tunica vaginalis testis. However, malignant mesothelioma of the liver is extremely rare and coexistence with malignant mesothelioma of the greater omentum has not been described in the literature. In this case report, we present a case of multiple malignant mesothelioma of the liver and greater omentum.
A 36-year-old woman was admitted to our hospital for the evaluation of an elastic hard mass in the right upper abdomen. Abdominal contrast computed tomography showed a cystic mass measuring 13 × 14 × 11 cm in the right liver lobe with enhanced mural nodule. Abnormal accumulation was identified in the liver and lower abdominal area on 18F-fluorodeoxyglucose positron emission tomography. The patient underwent hepatectomy of the posterior segment and partial resection of the omentum. The final pathological diagnosis was low-grade multiple malignant epithelioid mesothelioma based on characteristic immunohistochemical findings. As of 6 months postoperatively, the patient has shown no disease recurrence.
We present the first case of a 36-year-old woman with multiple malignant mesothelioma of the liver and greater omentum.
Malignant mesothelioma commonly arises from the mesothelial surfaces of the pleural cavities and is usually associated with inhalation of asbestos fibers . In contrast, peritoneal malignant mesothelioma is a rare disease, and malignant mesothelioma arising in the liver is extremely rare [2–12]. Moreover, malignant mesothelioma of the greater omentum is also extremely rare [13, 14]. We present herein the case of a 36-year-old woman with multiple malignant mesothelioma of the liver and greater omentum.
Summary of hepatic mesothelioma
Data (n = 12)
Mean age (range)
58.4 years (41–68 years)
1 (C type)/9/2
Mean tumor size (range)
12.2 cm (3.2–24 cm)
2 (Lymph node)/5/5
We presented the case of a 36-year-old woman with multiple malignant mesothelioma of the liver and greater omentum with review of the literatures.
We declare that each author received no funding for this study.
Availability of data and materials
The datasets supporting the conclusions are included within the article.
KM, HO, and KH participated in the surgery, collected the data and consent, and drafted the manuscript. SM performed the pathological examinations and participated in drafting the manuscript. YO, TS, KM, YS, and MS participated in the surgery. IK diagnosed the radiological findings and participated in the drafting of the manuscript. YB performed the physical diagnosis. SN participated in the design, coordination, and drafting of the manuscript. All authors read and approved the final manuscript.
The authors declare that they have no competing interests.
Consent for publication
The patient consented to the publication of the features of her case, and her identity has been protected.
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