Fig. 3

Computed tomography (CT) in Case 1. Arrows, primary gastric tumor; red arrowheads, liver metastases; blue arrowheads, lesions of interstitial pneumonia. A Before starting chemotherapy, the gastric tumor extends from the lower body to the pylorus of the stomach. B Liver metastases of up to 6.0 cm are observed. C CT of the lungs reveals no obvious lesions. D CT shows a reduction in the primary tumor after 3 cycles of SOX therapy. However, after two cycles, a metallic stent is inserted into the tumor. E CT shows a reduction in the liver metastases after 3 cycles of SOX therapy. F CT after 44 cycles of SOX therapy shows reticular and ground-glass opacities in both lung fields. G Sixty-six months after starting chemotherapy, CT shows significant shrinkage of the primary tumor. The metallic stent migrated and disappeared from the gastric pylorus. H CT shows significant shrinkage of the liver metastases. I Three months after stopping SOX therapy, CT shows an improvement of the interstitial lesions in both lungs