Fig. 3
Macroscopic and microscopic findings of the resected specimen: macroscopic images of the resected specimens of S8 (A) and S7 (B). Microscopic images of the resected lesion with hematoxylin and eosin (HE) staining are shown in C (C-1, loupe view; C-2, magnified by Ă—100; C-3, magnified by Ă—200). The ill-defined lesion is pointed by some yellow arrowheads (C-2). Central venous area of the lesion is magnified by Ă—400 (C-3). The yellow arrowhead indicates the central vein, and loss of hepatocyte and congestion is observed (C-3). Accumulated macrophages around the central vein are revealed by CD68 stain (D). Non-specific mild lymphocytic infiltrate is observed at the periportal region with HE staining (E). The red arrowhead indicates the portal vein. The yellow arrowheads indicate the dense reticular fibers with atrophic hepatocytes surrounding the central veins by silver staining at the lesion (F)