Table 1 Spontaneous regression (SR) of small cell lung cancer: a review of literature
First author | Years | Age | Sex | Biopsy before SR | Shrinkage percentage (duration) | Treatment modality after SR | Stage | OS (months) | |
|---|---|---|---|---|---|---|---|---|---|
1 | Shibata7 | 2021 | 83 | F | TBNA | 100% (7 years) | BSC | Unknown | 108 |
2 | Song8 | 2021 | 80 | M | Bronchoscopic biopsy | Unknown (52 months) | BSC | Unknown (LD) | 53 |
3 | Ugajin9 | 2019 | 82 | M | TBLB | 100% (18 months) | BSC | c-IIIB | 18 |
4 | Inui10 | 2015 | 69 | F | TBLB | 37.5% (unknown) | Surgery (segmentectomy) Adjuvant chemotherapy (CDDP + ETP) | p-IA | 27 |
5 | Kitai11 | 2014 | 65 | F | EBUS–TBNA | Unknown (unknown) | Chemotherapy (CDDP + ETP) | c-IIIB | Unknown |
6 | Iwakami12 | 2013 | 56 | F | VATS biopsy | Partial regression (30 days) | CRT (CDDP + ETP and RT) | c-IIIB | 25 |
7 | Mawhinney13 | 2010 | Elderly | F | biopsy | Partial regression (7 months) | BSC | Unknown | 18 |
8 | Lee14 | 2008 | 70 | F | Bronchoscopic biopsy | 100% (unknown) | BSC | c-IIIA | 132 |
9 | Hirano15 | 2007 | 55 | F | TBLB | Partial regression (1 month) | CRT (CDDP + ETP and RT) | c-IIIA | Unknown |
10 | Lowy16 | 1986 | 55 | M | Node biopsy | Unknown (6 months) | BSC | Unknown | 228 |
11 | Our case | 78 | F | CT-guided PTNB | 95.8% (1 month) | Surgery (lobectomy) | p-IA1 | 23 |