Report | Synchronous or metachronous metastases | The site of metastases | Primary surgery for metastatic tumor | Preoperative chemotherapy | Clinical course | Reported survival |
---|---|---|---|---|---|---|
Butturini et al. [4] | Synchronous | Liver metastasis | Liver metastasis excision | Unspecified | Recurrence and death with primary disease | 31 months (dead) |
Butturini et al. [4] | Metachronous | Liver metastasis | Liver metastasis excision | gemcitabine | No recurrence | 85 months |
Armstrong et al. [11] | Synchronous | Solitary liver metastasis | RFA | No | Recurrence at liver treated with RFA and systemic chemotherapy (capecitabine, imatinib, etoposide, and doxorubicin), and at mesenteric lesions with systemic chemotherapy (sorafenib and temozolomide) | 96 months (dead) |
Cananzi et al. [12] | Synchronous | Five liver metastases | Right hemi-hepatectomy | Docetaxel, irinotecan and cetuximab | Recurrence at liver, para-aortic lymph node, peritoneal and retroperitoneal tissue, adrenal gland, and brain. Liver metastases were treated with surgery and RFA. The other metastases were all resected Newly detected liver metastases were treated with chemotherapy (nab-paclitaxel and panitumumab) | 132 months |
Di marco et al. [13] | Metachronous | Three liver metastases | RFA | Gemcitabine plus capecitabine | No recurrence | 68 months |
Di marco et al. [13] | Metachronous | Two liver metastases | RFA | Gemcitabine plus capecitabine | Recurrence at peritoneal tissue treated with systemic chemotherapy (capecitabine plus irinotecan, gemcitabine plus capecitabine) | 86 months (dead) |
Hashimoto et al. [14] | Synchronous | Two liver metastases | Left hemi-hepatectomy and partial resection | No | Recurrence at liver (partial liver resection and hepatic arterial infusion with 5-FU, cisplatin, and mitomycin C) | 63 months |
Jauch et al. [15] | Synchronous | Solitary liver metastasis | Right hemi-hepatectomy | Capecitabine plus oxaliplatin | Recurrence at liver (complete eradication by chemotherapy) | 42 months |
Maehira et al. [16] | Metachronous | Multiple liver metastases, local recurrence | The removal of multiple liver metastases and local recurrence in the pancreatic bed | Cisplatin plus irinotecan | No recurrence | 57 months |
Ohara et al. [17] | Metachronous | Solitary liver metastasis, rectum | Right posterior sectorectomy and abdominoperitoneal resection | No | No recurrence | 40 months |
Sumiyoshi et al. [18] | Synchronous | Peritoneal dissemination | Resection of disseminated nodule | No | No recurrence | 73 months |
Suzuki et al. [19] | Metachronous | Four liver metastases | Extended left hemi-hepatectomy and partial resection | No | Recurrence at liver (partial liver resection for solitary metastasis) | 65 month |