Fig. 5

Histopathological features of the resected specimen. a Almost all the liver tumor was replaced by fibrous scarred tissues and tumor cells seemed no longer viable in the scarred area (Elastica Masson stain 20 ×). b The tumor cells in the pancreas were small-sized atypical cells with large nuclei forming acinar patterns. Acinar-like structures were more frequently observed in the pancreatic tumor than in the liver tumor (H&E 20 ×). c Tumor cells stained with trypsin in the liver tumor (trypsin 100 ×). d Tumor cells stained with trypsin in the pancreatic tumor (trypsin 100 ×)