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Table 3 Literature review

From: Two cases of unresectable hepatocellular carcinoma treated via atezolizumab and bevacizumab combination therapy

References

Year

Age

Gender

Etiology

BCLC

Unresectable reason

Size maximum (cm)

Regimen

Cycles

Pathological

f/u

Cancer-free/drug free

       

Pre

Post

  

Response

(month)

[6]

2021

68

M

Non-viral

C

Rt adrenal meta

72

ND

ATZ/BEV → LEN

4

PR

5

 + / + 

[7]

2021

63

M

ND

B

Tumor spread bilateral lobes

15.5

17.2

TACE → ATZ/BEV

15

PR

19

 + / + 

[8]

2022

79

M

ND

C

PVTT

ND

ND

ATZ/BEV + TAE

2

PR

5

 + / + 

[9]

2022

77

M

HBV

C

Rt adrenal meta, IVC invasion

15.2

9.9

ATZ/BEV

9

CR

3

 + / + 

[10]

2022

77

M

Non-viral

C

Lung meta

16.8

12.7

ATZ/BEV

7

CR

8

 + / + 

[11]

2023

75

M

ND

C

Peritoneal metastasis

5.7

4.7

ATZ/BEV + TAE

15

CR

7

 + / + 

Our case

2023

71

M

Non-viral

A

Remnant liver volume

12.5

7.3

ATZ/BEV

10

CR

12

 + / + 

Our case

2023

72

M

Non-viral

A

Remnant liver volume

11.6

6.4

ATZ/BEV

7

PR

5

 + / + 

  1. BCLC Barcelona Clinic Liver Cancer grade, ATZ/BEV atezolizumab and bevacizumab combination therapy, LEN lenvatinib, HBV hepatitis B virus, TACE transcatheter arterial chemoembolization, TAE transcatheter arterial embolization, PVTT portal vein tumor thrombosis, IVC inferior vena cava, ND no data