Table 1 NIH consensus guidelines
From: Retroperitoneal solitary neurofibroma mimicking lymph node metastasis of colon cancer: a case report
NIH consensus guidelines: diagnostic criteria for neurofibromatosis I |
|---|
Two or more of the following |
1. Six or more café-au-lait macules that are (in greatest diameter) > 5 mm in pre-pubertal individuals > 15 mm in post-pubertal individuals |
2. Two or more neurofibromas of any type, or one plexiform neurofibroma |
3. Axillary/inguinal freckling |
4. Optic glioma |
5. Two or more Lisch nodules |
6. Distinctive osseous lesion (i.e., sphenoid dysplasia or thinning of long bone cortex with or without pseudoarthrosis) |
7. First degree relative with NF-1 |