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Surgical Case Reports
Fig. 2 | Surgical Case Reports

Fig. 2

From: A long-term survival case of histiocytic sarcoma by surgery alone in a Japanese elderly breast tumor patient

Fig. 2

Characterization of the breast lesion. a Macroscopic finding. Round lesion showing well-defined margin, focal necrotic tissue, and bleeding. b Hematoxylin and eosin stain (HE), × 40. Proliferation of large, epithelioid cells with bizarre pleomorphic nuclei and abundant cytoplasm. HE, × 10. Prominent multinucleated giant cells showed scattered lymphocytes and eosinophils in the background. c Immunohistochemical panel. CD68, positive; CD163, positive; CD206, positive; AE1/AE3, negative; CD1a, negative

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