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Table 2 Coagulation data at the onset of coagulopathy

From: Fatal acquired coagulation factor V deficiency after hepatectomy for advanced hepatocellular carcinoma as a possible immune checkpoint inhibitor-related adverse event: a case report

Variable

Results

Reference range

Prothrombin time

 (s)

104.2

10.0–15.0

 (%)

< 7.0

70.0–130.0

PT-INR

> 7.02

0.85–1.30

Activated partial thromboplastin time (s)

123.9

23.5–35.0

Fibrinogen (mg/dL)

465

180–350

D-dimer (μg/mL)

6.1

0.0–1.0

Fibrin/fibrinogen degradation products (μg/mL)

9

0–5

Factor II activity (%)

< 6

70–120

Factor V activity (%)

< 6

70–140

Factor VII activity (%)

< 6

70–120

Factor VIII activity (%)

64

70–130

Factor IX activity (%)

11

70–120

Factor X activity (%)

< 6

70–120

Factor XI activity (%)

< 1

70–120

Factor XII activity (%)

21

70–150

Factor XIII activity (%)

87

70–130

Lupus anticoagulant

 SCT (screening) (s)

≥ 300

 

 SCT (confirmatory) (s)

≥ 240

 

 The normalized SCT ratio

N.D

< 1.16

Anti-cardiolipin-beta2-glycoprotein I complex antibody (U/mL)

≤ 1.2

< 3.5