Case report: administration of immune checkpoint inhibitor for SMARCB1 (INI1)-negative rhabdoid carcinoma with microsatellite instability (MSI)-high in the right colon

Surgical Case Reports

Table 1 Clinicopathological features of SMARCB1-negative rhabdoid carcinoma of the colorectum

Author	Age (years)	Sex	Location	Size (cm)	RAS/BRAF^V600E status	EGFR expression	SMARCAB1	MSI Status	Treatment	Metastasis	Outcome
Pancione et al. [6]	73	Female	Right-side colon	10 × 8	RAS wild/ BRAF^V600E mutation	Negative	Loss	High	Surgery, capecitabine, oxaliplatin	Liver	DOD 6 months
Agaimy et al. [1]	79	Male	Cecum	9 × 5 × 2	RAS wild/ BRAF^V600E mutation	NA	Loss	High	Surgery	LN	DOD 6 months
D'Amico et al. [7]	65	Male	Cecum	10 × 8 × 10	NA	NA	Loss	NA	Surgery, chemotherapy	LN	AWD 48 months
Tessier-Cloutier et al. [2]	81	Female	NA	NA	NA	NA	Loss	MLH1, MSH2, PMS2( +), MSH6(-)	NA	NA	NA
Kojima et al. [8]	41	Male	Sigmoid colon	7 × 6	RAS wild/ BRAF^V600E mutation	NA	Loss	Stable	Surgery, FOLFOX6, FOLFOXIRI	Liver, peritoneum, LN	DOD 2 months
Present Case	71	Female	Right-side colon	7.5 × 7	RAS wild/ BRAF^V600E mutation	NA	Loss	High	Pembrolizumab	LN	DOD 3 months

NA not available, AWD alive without disease, DOD died of disease, LN lymph node