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Fig. 3 | Surgical Case Reports

Fig. 3

From: Epstein–Barr virus-associated inflammatory pseudotumor variant of follicular dendritic cell sarcoma of the liver: a case report and review of the literature

Fig. 3

EBER–ISH and immunohistochemistry for EBV-associated FDCS (scale bars = 25 µm). a Lesion is composed of atypical spindle cells admixed with infiltrating inflammatory cells on hematoxylin and eosin staining. b Nucleus of the spindle cells is diffusely positive for EBER–ISH. c Cytoplasmic positivity for CD23. d Double staining for CD23 immunohistochemistry (brown) and EBER–ISH (red) revealing that EBER–ISH positive cells show CD23 immunoreactive cytoplasm. EBER: Epstein–Barr virus enucleated RNA; ISH: in-situ hybridization; FDCS: follicular dendritic cell sarcoma

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