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Surgical Case Reports
Fig. 1 | Surgical Case Reports

Fig. 1

From: Report of two patients in whom comparisons of the somatic mutation profile were useful for the diagnosis of metastatic tumors

Fig. 1

Histopathological examination of biopsy specimens. Specimens from a gastric tumor biopsy (a–c), lung tumor biopsy (d–g), and mediastinal lymph node biopsy (h–l). Histopathological examination of the gastric tumor biopsy specimen showed poorly differentiated adenocarcinoma (hematoxylin–eosin staining) (a). The tumor cells of the gastric tumor were positive for cytokeratin (CK)7 (b) and negative for CK20 (c). Biopsy of the lung tumor showed invasive adenocarcinoma (hematoxylin–eosin staining) (d). Part of the tumor was tubular adenocarcinoma with mucus production. The tumor cells of the lung tumor were positive for CK7 (e), negative for CK20 (f), and negative for TTF-1 (g). Biopsy of the mediastinal lymph node showed poorly differentiated adenocarcinoma without a gland duct (hematoxylin–eosin staining) (h). The tumor cells of the mediastinal lymph node were positive for CK7 (i), negative for CK20 (j), positive for TTF-1 (k), and focally positive for p40 (l)

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