Skip to main content

Table 2 Previously reported cases of PEG-associated vasculitis

From: Pegfilgrastim-induced vasculitis of the subclavian and basilar artery complicated by subarachnoid hemorrhage in a breast cancer patient: a case report and review of the literature

Reference Year Age (years) Sex Primary disease Symptoms CRP (mg/dL) Time between PEG administration and symptoms (days) Location of vasculitis Diagnostic modality Steroid
Fever Other
Koyama et al. [19] 2021 43 F Breast cancer +   27.1 5 Arch/TA CT PSL 60 mg
Fujiwara et al. [20] 2021 66 F Colon cancer + Back pain 20.2 2 Arch/TA, SCA CT PSL 30 mg
Kametani et al. [21] 2021 56 M Mucinous chondrosarcoma + General fatigue, rash with pain 38.8 4 Arch/TA CT PSL 60 mg
Saito et al. [22] 2021 71 F Intrahepatic cholangiocarcinoma + Back pain, chest pain 18.9 7 Arch/TA CT PSL 30 mg
Jimbo et al. [1] 2021 58 F Breast cancer +   13.7 8 SCA CT None
Lee et al. [7] 2020 66 F Breast cancer + Myalgia, chills, nausea 26.6 13 Arch/TA, AA, CCA, innominate artery CT PSL 0.5 mg/kg
49 F Breast cancer + Myalgia, chest discomfort, dyspepsia 21.8 15 Arch/TA, CCA CT, PET/CT PSL 0.5 mg/kg
50 F Breast cancer + Myalgia, chills 29.6 12 Arch/TA, CCA, SCA, innominate artery CT PSL 0.5 mg/kg
59 F Breast cancer + Myalgia, chills 32.9 17 Arch/TA, AA, CCA, innominate artery CT PSL 0.5 mg/kg
53 F Breast cancer + Myalgia, chills, headache 10.9 14 Arch/TA, CCA CT PSL 0.5 mg/ kg
Nakamura et al. [23] 2020 66 F Breast cancer + Left anterior neck pain 8.2 11 CCA CT None
Mukai et al. [24] 2020 66 F Breast cancer + Malaise, abdominal discomfort 20.4 10 Arch/TA, AA CT, MRI PSL 55 mg
Taimen et al. [8] 2020 53 F Breast cancer + Chest pain, sore throat, earache, dyspnea Unknown 1 Arch/TA CT, MRI Corticosteroid
Miyazaki et al. [25] 2020 65 F Pancreatic cancer +    8 Arch/TA CT None
Hoshina et al. [26] 2019 72 F Breast cancer +   46.4 4 Arch/TA PET/CT None
Yukawa et al. [27] 2019 71 F Endometrial cancer +   27.9 4 Arch/TA CT PSL 60 mg
Sasaki et al. [28] 2019 69 M Non-Hodgkin lymphoma +   21.4 13 SCA CT None
Lardieri et al. [29] 2018 72 F Uterine cancer   Cough, lumbar and back pain 30.1 13 Aorta CT None
   76 F Breast cancer + Precordial pain 35.9 7 Aorta CT None
   61 F Breast cancer + Left neck pain 25.4 7 Aorta CT, MRI None
   65 F Breast cancer + Chest tightness, cough 30.8 9 Aorta CT Steroid
   66 M Prostate cancer +   33.3 8 Aorta CT None
   69 F Esophageal cancer +    11 Aorta CT, US None
Sato et al. [6] 2017 67 F Lung cancer + Malaise 20.2 8 Arch/TA, CCA CT, US mPSL 80 mg
Present case 2022 48 F Breast cancer + Malaise, left neck pain 12.65 14 Arch/TA, AA, CCA CT, US PSL 40 mg
  1. AA abdominal aorta, Arch aortic arch, CCA common carotid artery, CRP C-reactive protein, CT computed tomography, F female, M male, mPSL methylprednisolone, MRI magnetic resonance imaging, PEG pegfilgrastim, PET positron emission tomography, PSL prednisolone, SCA subclavian artery, TA thoracic aorta, US ultrasonography