Table 1 Synopsis of published cases of thyroid myxofibrosarcoma
From: Primary thyroid gland myxofibrosarcoma: a case report and review of the literature
Author | Patient | Symptoms | Radiological findings | FNAC | Therapy | Resection margins | Follow up |
|---|---|---|---|---|---|---|---|
Darouassi et al. [6] | 74-year-old female | Left lateral cervical swelling of 2Â months evolution | Ultrasound and CT scan: tumor process in the left thyroid lobe, ipsilateral submandibular lymphadenopathy | Not mentioned | Surgery: total thyroidectomy with tumor resection and ipsilateral functional lymph-node dissection; Chemotherapy: doxorubicin and ifosfamide for recurrence (6 cycles) | Negative | Local recurrence after 1Â month |
Salama et al. [7] | 76-year-old female | Rapidly enlarging left lower neck mass, dyspnea | Ultrasound: bilateral heterogeneous thyroid nodules, left lobe 7.1 × 4.5 cm, right lobe: 1.4 × 1.6 cm; CT-scan: left lobe: large solid mass, 7 × 6x5 cm with heterogeneous enhancement and cystic degeneration, no calcification | Spindle cell proliferation of moderate cellularity, occasional blood vessel fragments embedded in myxoid background. Moderately atypical spindle-shaped nuclei with moderate amount of ill-defined cytoplasm. Few scattered large bizarre cells with eccentric hyperchromatic nuclei and abundant cytoplasm. Cytological diagnosis: anaplastic thyroid carcinoma | Surgery: total thyroidectomy; Radiotherapy (postoperative) | Close to the circumferential margins | Not mentioned |
Kouassi et al. [8] | 45-year-old female | Pre-existing goiter with increasing swelling, dysphonia, hoarseness | Ultrasound: confirmation of the tumor, no lymphadenopathy | Not mentioned | Surgery: total thyroidectomy, right sternocleidomastoid muscle and laryngeal nerve resection | Not mentioned | Not mentioned |
Zhang et al. [9] | 65-year-old male | Not mentioned | Not mentioned | Not mentioned | Not mentioned | Not mentioned | Dead of disease |