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Fig. 4 | Surgical Case Reports

Fig. 4

From: Spontaneous rupture of an undifferentiated carcinoma with osteoclast-like giant cells of the pancreas presenting as intra-abdominal bleeding: a case report

Fig. 4

Histopathological findings of the resected specimen. a Hematoxylin and eosin, ×40. Scale bar = 500 µm. The site of the rupture (arrow). Intra-tumoral hemorrhage (arrowhead). b Hematoxylin and eosin, ×200. Non-neoplastic osteoclast-like giant cells were present (square). Scale bar = 200 µm. c Hematoxylin and eosin, ×200. Round to spindle-shaped, highly pleomorphic mononuclear cells as well as a component of ductal adenocarcinoma were seen. Scale bar = 200 µm. d Elastic fiber staining, ×40. Scale bar = 500 µm. Extensive tumor infiltration into the splenic vein was present (yellow circle). e Immunohistochemical examination showed that the tumor cells were negative for cytokeratin AE1/AE3, ×40. Scale bar = 500 µm. f The non-neoplastic osteoclast-like giant cells were positive for CD68 (square), ×40. Scale bar = 500 µm

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