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Table 1 Description of case studies from the literature

From: Gastric cancer complicated by paraneoplastic neurological syndrome which presented with extremity numbness: a case report

References

Age/sex

Time to diagnosis

Clinical syndrome

Histological type

Onconeural antibody

Neurological outcome

Oncological outcome

Balducci et al. [18]

58/male

1 month

PCD

Neuroendocrine

N/A

Partial response (OP + IT)

Disease free (18 months)

Kikuchi et al. [19]

63/male

N/A

PCD

Neuroendocrine

Ri

N/A

N/A

Baraller et al. [20]

59/male

1 month

OMS

N/A

N/A

No response (IT)

Dead (6 months)

Meglic et al. [21]

73/male

4 months

PCD

Poorly

Yo

No response (OP)

Disease free (6 months)

Wada et al. [22]

64/male

9 months

PLE

Neuroendocrine

Not detected

No response (CT)

Dead (19 months)

Tanaka et al. [23]

77/male

2 months

PLE

N/A

GluR

Progressive

(No treatment)

Alive (3 months)

Goto et al.[24]

71/male

-7 months

PCD

N/A

Yo

No response (IT)

Disease free (2 months)

Yasuda et al. [25]

72/female

24 months

SSN, SM

Signet-ring cell

N/A

Complete response (OP + IT)

Disease free (36 months)

Murakami et al. [26]

63/female

5 months

SSN

Neuroendocrine moderate

Hu

Partial response (OP + CT + IT)

Disease free (31 months)

Taketa et al. [3]

72/male

0.5 months

PLE

Neuroendocrine

N-type VGCC

Complete response (OP + CT)

Disease free (15 months)

Biotti et al. [26]

61/male

3 months

PLE

Adenocarcinoma

Ma

Partial response (CT + IT)

Alive (9 months)

Al-Harbi et al. [28]

38/female

2 months

PLE

Neuroendocrine

N/A

Partial response (IT)

N/A

Bataller et al. [29]

59/male

N/A

OMS

Adenocarcinoma

N/A

No response (IT)

Dead (6 months)

Uneno et al. [30]

71/male

N/A

PLE

Adenocarcinoma

Hu

Partial response (CT)

Dead (14 months)

Our case

70/female

1 months

LEMS

Adenocarcinoma

N/A

Complete response (OP + IT)

Disease free (24 months)

  1. N/A not applicable; PCD paraneoplastic cerebellar degeneration; OMS opsoclonus–myoclonus; PLE paraneoplastic limbic encephalitis; SSN subacute sensory neuropathy; SM systematic myositis; VGCC voltage-gated calcium channel; LEMS Lambert–Eaton myasthenic syndrome; OP operation; IT immunotherapy; CT chemotherapy; GluR glutamate receptor