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Surgical Case Reports
Fig. 4 | Surgical Case Reports

Fig. 4

From: Conversion surgery following gemcitabine plus cisplatin therapy for initially unresectable gallbladder cancer with peritoneal carcinomatosis: a case report

Fig. 4

a The primary carcinoma of the gallbladder showed papillotubular growth in the mucosa (top) and the invaded site (left bottom). Squamous differentiation was partially present in the invaded site (right bottom). b The squamous cell carcinoma (SCC) component (right side) was smoothly differentiated from adenocarcinoma (left side). c Nuclei of SCC cells were positive for p40 in immunohistochemistry. d Lymphatic invasion was seen in the perimuscular connective tissue layer of the gallbladder. e The adenocarcinoma component of the gallbladder showed degenerative features such as atrophic changes of tumor cells and prominent fibrosis and calcification of the surrounding stroma. f Similar degenerative changes were present in the metastatic carcinoma of the omentum

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