Pathological complete response achieved by gemcitabine plus cisplatin therapy for initially unresectable advanced gallbladder cancer: a case report

Surgical Case Reports

Table 2 The cases achieved a pathological complete response for advanced biliary tract cancer

No	Author reference (year)	Age (years)	Sex	Disease			Preoperative chemotherapy		*Interval (months)		Postoperative Survival (months)		Adjuvant chemotherapy		Recurrence, Status
1	Sharma et al. [5] (2010)	N/A	N/A	GBC			GEM + oxaliplatin		N/A		N/A		N/A		N/A, N/A
2	Moussata et al. [6] (2012)	58	F	GBC			GEM + oxaliplatin		5		14		None		Local recurrence (lymph node metastasis), Alive
3	Lim et al. [17] (2013)	58	M	Extrahepatic cholangiocarcinoma			GEM + S − 1		7		3		None		None, alive
4	Walker et al. [18] (2014)	64	M	Extrahepatic cholangiocarcinoma			GC		2		18		None		None, alive
5	Hashimoto et al. [7] (2014)	47	F	GBC			GC		6		14		S-1		None, alive
6	Kato et al. [8] (2014)	59	F	GBC			GC		6		11		None		None, alive
7	Matsubara et al. [19] (2016)	68	F	Hilar cholangiocarcinoma			GC + S-1		6		9		None		None, alive
8	Watanabe et al. [20] (2017)	70	F	Extrahepatic cholangiocarcinoma			GEM + S − 1		24		48		5 courses of GC		None, alive
9	Present case	71			F	GBC		GC		49		24		None		None, alive

GBC gallbladder cancer, GEM gemcitabine, GC gemcitabine plus cisplatin, S − 1 tegafur/gimeracil/oteracil
*Interval to surgery from the first chemotherapy