Fig. 2

Pathological findings. Almost of all breast cancer lesions had intraductal cribriform structures. There was small invasive lesions with mucus representing stromal infiltration (a, HE ×200). ER positive (b), PgR positive (c) and HER2 negative (1+) (d). Renal tumor had proliferative tumor cells with ductal and cribriform structures, and the tumor cells are similar to those of breast cancer (e, HE ×400). ER positive (f), PgR positive (g) and HER2 negative (2+, FISH negative) (h) for renal tumor. Cells in lung tumor were also similar to those of breast cancer (i, HE ×400). ER positive (j), PgR positive (k) and HER2 negative (2+, FISH negative) (l) for lung tumor. Both TTF-1 and Napsin-A were negative (not shown)