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Surgical Case Reports
Fig. 4 | Surgical Case Reports

Fig. 4

From: Tumor-to-tumor metastasis: an extremely rare combination with renal cell carcinoma as the donor and a pancreatic neuroendocrine tumor as the recipient

Fig. 4

Histopathological findings of the pancreatic tumor which exhibited TTM combined with neuroendocrine tumor and RCC. a Overall view of the pancreatic tumor with HE stain. The tumor was composed of two different components which were divided into the central and peripheral areas. b Boundary area of the central and peripheral area. Left side area from the yellow arrowhead showed central area in the pancreatic tumor; this area composed the same findings to clear cell RCC of the left kidney tumor. Right side from the yellow arrowhead area showed peripheral area in the pancreatic tumor; this area was considered as neuroendocrine tumor. c The peripheral area of the pancreatic tumor with HE stain of a high power field figure. Medium-sized tumor cells with fine granular cytoplasm and round nucleus made ribbon-like regular cord structures. We diagnosed with this area tumor as PNET. d Positive for synaptophysin stain in the peripheral area, whereas negative in the central area. e Negative for CD10 stain in the peripheral area, whereas positive in the central area

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