Fig. 2

Course of platelet count, anticoagulation therapy, and PF4/H antibody. Platelet count reduced to 7.8 × 10⁴/μl on POD 2 and recovered gradually. Argatroban was initiated 3 h postoperatively and continued until POD 6. Warfarin was also started when platelet count exceeded 10 × 10⁴/μl on POD 4 and continued for 3 months. PF4/H Ab turned positive on POD 8, but disappeared 91 days later. POD, postoperative day; PF4/H Ab, platelet factor-4/heparin antibodies