Fig. 1From: Off-pump coronary artery bypass with heparin in a patient with a history of heparin-induced thrombocytopenia: a case reportCourse of ACT and anticoagulation. Course of ACT and anticoagulation. Dual antiplatelet therapy was converted to argatroban preoperatively. The dose of heparin and the reaction of ACT were as usual. Clot formation was observed in the surgical field when the ACT was around 300 s. Even when sufficient protamine was used, the ACT was prolonged. ACT, activated clotting timeBack to article page