Fig. 2

Microscopic findings of neuroendocrine composite hemangioendothelioma. a The epithelioid portion of the tumor was consisted of a sheet-like proliferation of uniform, small, epithelioid endothelial cells (H&E, ×20). b In the retiform area, the tumor was composed of elongated, branching vascular channels lined by monotonous, hobnailing endothelial cells (H&E, ×20). Thus, this case was diagnosed as composite hemangioendothelioma. The tumor cells showed diffuse and strong immunoreactivity for CD31 (c; ×40), and synaptophysin (d; ×40). H&E hematoxylin and eosin staining