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Surgical Case Reports

Table 1 Changes in neutrophils after the first pegfilgrastim administration (n = 21)a,b

From: Drug-induced aortitis of the subclavian artery caused by pegfilgrastim: a case report

 

Day 0c,d

Day 14c,d

P value

WBC

5395 (2700–8500)

10,838 (5500–19,200)

< 0.001

Neutrophil rate

57.3% (41.8–67.1)

77.2% (59.2–84.2)

< 0.001

Absolute neutrophil count

3126 (1463–5542)

8492 (3300–15,110)

< 0.001

CRP

0.10 (0.03–0.63)

0.37 (0.02–1.45)

0.011

  1. aMean age was 49.8 (range 33–64). bAll patients were given dose-dense EC (E: epirubicin 90 mg/m2, C: cyclophosphamide 600 mg/m2) and pegfilgrastim (3.6 mg) was administered 1–3 days later. cThe day of the first dose-dense EC administration was counted as Day 0. dMean (range)
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