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Table 1 Changes in neutrophils after the first pegfilgrastim administration (n = 21)a,b

From: Drug-induced aortitis of the subclavian artery caused by pegfilgrastim: a case report

  Day 0c,d Day 14c,d P value
WBC 5395 (2700–8500) 10,838 (5500–19,200) < 0.001
Neutrophil rate 57.3% (41.8–67.1) 77.2% (59.2–84.2) < 0.001
Absolute neutrophil count 3126 (1463–5542) 8492 (3300–15,110) < 0.001
CRP 0.10 (0.03–0.63) 0.37 (0.02–1.45) 0.011
  1. aMean age was 49.8 (range 33–64). bAll patients were given dose-dense EC (E: epirubicin 90 mg/m2, C: cyclophosphamide 600 mg/m2) and pegfilgrastim (3.6 mg) was administered 1–3 days later. cThe day of the first dose-dense EC administration was counted as Day 0. dMean (range)