Table 1 Characteristics of serous cystadenocarcinoma of the pancreas
Case | Author | Year | Age/sex | Size (cm) | Signs or symptoms | Metastases (single/multiple liver metastases) | Synchronous/metachronous (time interval from initial treatment) | Treatment for metastases | Outcome (time after diagnosis of metastases) |
|---|---|---|---|---|---|---|---|---|---|
1 | George et al. [2] | 1989 | 70/M | 11 | Hemorrhage from gastric varices | Liver (multiple) | Synchronous | None | Intraoperative death due to blood loss |
2 | Friedman et al. [13] | 1990 | 74/F | 19 | Right flank pain, weight loss, abdominal mass | Liver (multiple), lung, bone, adrenal glands | Synchronous | None | Dead of primary disease |
3 | Okada et al. [14] | 1991 | 63/F | 12 | Abdominal pain | Liver (multiple) | Metachronous (4 years) | Partial hepatectomy | Alive (NR) (1 year) |
4 | Yoshimi et al. [15] | 1992 | 63/F | 12 | abdominal mass, epigastric pain | Liver (multiple) | Metachronous (3 years) | Partial hepatectomy | Alive (NR) (3 years) |
5 | Ishikawa et al. [16] | 1998 | 63/F | 12 | Abdominal pain | Liver (single) | Metachronous (3 years) | Partial hepatectomy | Not described |
6 | Eriguchi et al. [17] | 1998 | 56/F | 16 | Abdominal mass | Liver (multiple) | Synchronous | MCN | Liver recurrence 9 years after MCN Alive (NR) 1 year after hepatectomy and repeated MCN for liver recurrence (10 years after initial metastasis) |
7 | Wu et al. [18] | 1999 | 57/F | No data | Incidental finding | Liver, (multiple) peritoneum | Metachronous (10 years) | None | Not described |
8 | Strobel et al. [19] | 2003 | 56/F | 14 | Abdominal pain, diarrhea, weight loss | Liver (single) | Metachronous (3 years) | Partial hepatectomy | Alive (NR) (3 years) |
9 | Franko et al. [20] | 2008 | 68/F | 5 | Hemorrhage from gastric varices, abdominal pain, weight loss | Liver (multiple) | Metachronous (3 years) | None | Dead of primary disease (9 months) |
10 | Bano et al. [21] | 2011 | 62/M | 7 | Abdominal pain, vomiting, weight loss | Liver (multiple) | Metachronous (1 year) | MCN | Alive (NR) (1 year) |
11 | Bramis et al. [22] | 2012 | 86/F | 17 | Abdominal pain | Liver (multiple) | Synchronous | None | Dead of unrelated disease (1 month) |
12 | Wasel et al. [23] | 2013 | 68/M | 12 | Incidental finding | Liver (multiple) | Synchronous | 4 months of chemotherapy | Alive (1 year) |
13 | Kainuma et al. [24] | 2015 | 69/M | 6 | Abdominal discomfort | Liver (multiple) | Synchronous | Partial hepatectomy | Alive (NR) (2.5 years) |
14 | Huh et al. [25] | 2016 | 52/F | 9 | Abdominal mass | Liver (multiple) | Metachronous (5 years) | None | Alive (1.5 years) |
15 | Van Dyke et al. [26] | 2016 | 78/M | 16 | Incidental finding | Liver (multiple) | Synchronous | RFA | MCN for liver recurrence 4.5 years after RFA Alive observing liver recurrence 15 months after MCN (6 years after initial metastasis) |
16 | Massaras et al. [27] | 2020 | 60/F | 9 | Incidental finding | Liver (single) | Synchronous | Sunitinib (4 cycles), partial hepatectomy | Alive (NR) (3 years) |