Table 1 Literature review: salvage surgery after dCRT with high-dose radiation

Age (y/o)^a

73

60

64

58

56.2

60–69

65.1

65.5

PreOP staging^b

IIIB

IIIA

III

IIIA

IIIA

IIIA

IIIA/B

IIIA

Smoking history^b

Former

N/A

N/A

Former

N/A

N/A

N/A

Former

Histology^b

SqCC

NSCLC

NSCLC

NSCLC

NSCLC

NSCLC/SCLC

NSCLC

SqCC

Radiotherapy dose (cGy)^a

9000

6390

5700

6000

6620

Mean 5800

6500

6000

dCRT to salvage OP (days)

164 (980)

147^a

N/A

123.9^a

211.4^a

210^a

250.6^a

279ǂ

Pre-operative FEV1 (L)

2.33

2.3^a

1.9^a

69%^c

N/A

N/A

N/A

N/A

Initially inoperable (No.)

1

8

2

8

1

14

12

8

Resection extent (Extended %)

Nil

20.8

28.6

19.4

78

45

N/A

37

Sublobar

–

–

3

–

1

–

–

–

Lobectomy

–

10

8

30

6

11

7

6

Bilobectomy

1

4

–

1

1

1

7

–

Sleeve lobectomy

–

–

1

–

–

–

–

–

Pneumonectomy

–

10

2

-

1

17

14

5

Exploratory only

–

–

–

–

–

6

–

–

Approach (open/VATS)

VATS

Open

Open

Open^b

Open^b

Open

Open

Open

Operating time (hour)^a

6.5

5.5

N/A

N/A

3.9

N/A

N/A

4.9

Estimated blood loss (ml)^a

50

250

N/A

N/A

400

N/A

N/A

150

Morbidity/mortality (%)

0

58.3(4.2)

43(0)

48(0)

22(11)

51(5.7)

14.8(3.7)

57(6.7)

Hospital stay after OP (days)^a

8

8

10

4

20

7

8

7

Survival (months)^a

42(7^d)

3^d

9^d

32.5^d

23^d

13

75.6

24