Three resected cases of esophageal carcinoma considered as being secondary solid tumors after bone marrow transplantation

Surgical Case Reports

Table 1 Characteristics of the 3 cases

	Sex	Age when EC was diagnosed	pStage of EC	Hematological disorders	Donor	Immunosuppressants	Radiation	Chronic GVHD	Period from BMT to EC diagnosed
Case 1	Female	40	T3N3M0, Stage III	Acute myeloid leukemia	HLA-matched sister	Cyclophosphamide, cyclosporine	12 Gy	Pulmonary complications	9 years
Case 2	Male	45	T3N2M0, Stage III	Acute lymphocytic leukemia	HLA-matched sister	Cyclophosphamide, VP-16	13.2 Gy	Liver dysfunction	15 years
Case 3	Female	30	T3N2M0, Stage III	Fanconi anemia	Unrelated HLA-mismatched male	Cyclophosphamide, tacrolimus, methotrexate	3 Gy	Rash	15 years

EC, esophageal carcinoma; GVHD, graft-versus-host disease; BMT, bone marrow transplantation; HLA, human leukocyte antigen