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Surgical Case Reports
Fig. 3 | Surgical Case Reports

Fig. 3

From: IgG4-related gastric disease with plasma cell-rich obliterative arteritis accompanied by early-stage gastric cancer: a case report

Fig. 3

a Poorly differentiated adenocarcinoma with signet-ring cells had proliferated within the lamina propria (HE; original magnification, ×200). b The submucosal layer was expanded by fibrosis, lymphoid follicles, obliterative phlebitis, and arteritis (HE; original magnification, ×40). c A dense and diffuse infiltrate of plasma cells and lymphocytes (HE; original magnification, ×200). d Obliterative phlebitis is highlighted by Elastica staining (Elastica-Masson; original magnification, ×100). e Lymphoplasmacytic infiltrate is observed in the interstitium of the muscularis propria (HE; original magnification, ×100). f Immunostaining for IgG4 reveals infiltration by a large number of IgG4-positive plasma cells (original magnification, ×200)

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