Author (reference number), year | Age (years) | Sex | Symptoms and signs | Esophageal site of the tumor | Tumor type (macroscopic appearance on endoscopy) | Complication owing to esophageal involvement | Diagnostic method | Anaplastic lymphoma kinase (ALK) expression | Tumor stage per the Ann arbor classification | Treatment | Outcome | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Pearson JM et al. [6], 1991 | 73 | M | Fatigue, weight loss, fever | Lower thoracic | Infiltrative type | Esophageal dilation | Autopsy | Not described | IV | None | Death immediately after onset |
2 | Ross CW et al. [7], 1992 | 44 | F | Dysphagia, back pain | Upper thoracic | Protruding type | Severe esophageal stricture | Endoscopic biopsy of the esophagus | Not described | IV | Chemotherapy and radiotherapy | Lost to follow-up after 6 months |
3 | Yaakup H et al. [8], 2008 | 34 | F | Dysphagia | Upper thoracic | Protruding type (similar to hard fungating tumors) | Severe esophageal stricture | Endoscopic biopsy of the esophagus | Positive | IV | Chemotherapy, allo-SCT, and esophageal stenting | Being followed up for 24 months |
4 | Joshi A et al. [9], 2008 | 55 | M | Dysphasia, weight loss, sore throat | Cervical | Ulcerative type | Tracheoesophageal fistula | Endoscopic biopsy of the esophagus | Positive | III | Chemotherapy and allo-SCT | Not described |
5 | Wu N et al. [4], 2011 | 37 | M | Dysphagia, weight loss | Middle thoracic | Protruding type (submucosal tumor) | None | Esophagogastrostomy | Positive | III | Esophagectomy and adjuvant chemotherapy | Being followed up for 14 months |
6 | Hryhorczuk AL et al. [10], 2012 | 3 | M | Abdominal pain, vomiting | Upper thoracic | Not described | Esophageal obstruction and perforation | Axillary lymph node biopsy | Positive | III | Chemotherapy | Not described |
7 | Azarpira N et al. [11], 2017 | 16 | M | Dysphagia | Middle thoracic | Infiltrative type | Severe esophageal stricture | Endoscopic biopsy of the esophagus | Positive | III | Chemotherapy and esophageal dilatation | Not described |
8 | Current case | 11 | M | Abdominal pain, cough, dysphagia | Middle thoracic | Infiltrative type | Esophageal atresia | Chest effusion cytology | Positive | IV | Chemotherapy, allo-SCT, and esophagectomy | Being followed up for 47 months |