Fig. 3

Microscopic findings of the type 2 tumor. a The type 2 tumor predominantly showed solid or cribriform proliferation of tumor cells with clear cytoplasm, which was moderately differentiated adenocarcinoma with enteroblastic-like differentiation (hematoxylin-eosin staining). The tumor cells of the adenocarcinoma component had periodic acid-Schiff (PAS)-positive globules (b) and were positive for sal-like protein 4 (SALL 4) (c) and negative for α-fetoprotein (AFP) (d) and human epidermal growth factor receptor type 2 (HER2) (e)