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Surgical Case Reports
Fig. 4 | Surgical Case Reports

Fig. 4

From: A patient with colitis-associated cancer who developed clinically manifest Crohn’s disease only after surgery

Fig. 4

Microscopic findings of the main tumor (a HE ×10, b HE ×10, c p53 ×10, d HE ×20). The surface area of the main tumor showed proliferation of atypical gland of either villous (a) or tubular pattern (b) in the mucosa. c Immunohistochemistry reveals that nearly 100% atypical glands in the surface area overexpression of p53. These observations confirmed the diagnosis of dysplasia in the surface area. d Atypical gland indistinguishable from dysplasia invaded the muscularis propria (well-differentiated adenocarcinoma)

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