Major criteria | Minor criteria |
---|---|
Arterial, digestive or uterine fragility or rupture | Positive family history or sudden death in a close relative |
Thin, translucent skin | Acrogeria |
Extensive bruising | Hypermobility of small joints |
Characteristic facial appearance | Tendon and muscle rupture |
Talipes equinovarus | |
Early-onset varicose veins | |
Spontaneous pneumothorax or haemothorax |