Adenocarcinoma originating from long-segment Barrett's esophagus over 15 cm: a series of 3 cases

Surgical Case Reports

Table 1 Characteristics of patients with LSBE larger than 15 cm

Case no.	Author	Year	Age	Gender	Length of Barrett's esophagus	Size of carcinoma (cm)	Location of the tumor	Histology	Depth of invasion	N	ly	V	Background disease	Prognosis
1	Kato	2002	45	M	15	2.7 × 2.3	Lt	tub2	SM	0	0	0	Hiatus hernia	2Y9M alive
2	Fujiwara	2006	67	F	18	5	UtMt	tub1	SM	0	2	0	Kyphosis, hiatus hernia	4Y8M alive
3	Fujiwara	2006	57	M	22	2	Lt	tub1	M	0	0	0	Post-total gastrectomy (R-Y, 29 years ago)	2Y alive
4	Stefan Hartl	2008	58	M	15	3	Lt	tub1	M	0	–	–	–	1M EMR, 4M additional operation
5	Shimada	2013	74	M	20	2.0 × 3.0	UtMt	tub1	M	0	–	–	Post-total gastrectomy (R-Y, 44 years ago)	1Y10M alive
6	Morita	2013	74	M	17	2.5 × 1.9	Ae	tub1	SM	0	0	0	Hiatus hernia	3Y alive
7	Kikuchi	2016	63	M	18	18 × 4	MtLt	tub1, pap > tub2, por	MP	0	0	0	Hiatus hernia	1Y6M alive
8	Zaiki	2016	65	M	15	12	LtMtAe	tub1	M	0	0	0	Hiatus hernia	1Y6M alive
9	Miyazaki	2016	68	M	17	11.6 × 4.9	LtMtAe	tub2 > tub1 > por	SM	0	1	0	Hiatus hernia	2Y5M died
10	Our case	2020	66	M	16	7 × 4.5	LtAe	por2 > sig	AD	N3	1	2	Hiatus hernia	2Y lymph node recurrence, alive
11	Our case	2020	83	F	15	6.0 × 5.2	Ut	tub1, tub1	AD	N3	2	2	Hiatus hernia	2M lymph node recurrence, died
12	Our case	2020	66	M	18	14.3 × 5.6	UtMtLtAeG	tub1	SM	0	0	0	Hiatus hernia	3M alive

tub1 well-differentiated tubular adenocarcinoma, tub2 moderately differentiated tubular adenocarcinoma, pap papillary adenocarcinoma, por poorly differentiated adenocarcinoma, M mucosal layer, SM submucosal layer, MP muscularis propria, AD adventitia, EMR endoscopic mucosal resection