Fig. 5From: Surgically resected primary esophageal choriocarcinoma accompanied with Barrett’s adenocarcinoma: a case reportMicroscopic and immunohistochemical findings of the choriocarcinoma. High magnification photomicrograph enclosed in a square in a is presented in b–n. The hemorrhagic portion contains large choriocarcinoma cells with syncytiotrophoblasts including condensed nuclei and an acidophilic cytoplasm (a, b). Strong hCG-positive staining was focally observed in syncytiotrophoblasts (c) and these cells were focally positive with p53, p40, SALL4, PLAP, CD146, EMA staining indicating a choriocarcinoma (d, f, g, h, m, n). These large cells were immunohistochemically negative for CK5/6, αSMA, glypican-3, AFP, Oct3/4, S100 and CEA (e, i, j, k, l, o, p)Back to article page