Table 2 Summary of 25 reported cases of primary extrahepatic bile duct neuroendocrine carcinoma
Sex (n=25) | Male | 20 | Operation (n =25) | ||
Female | 5 | Pancreatoduodenectomy | 12 | ||
Age (n=25) | median 70 years (range 28-84) | Bile duct resection | 9 | ||
Symptom | Jaundice | 22 | With hepatectomy | 4 | |
Abdominal pain | 6 | Lymph node metastasis (n=20) | |||
Weight loss | 3 | Positive | 12 | ||
Nausea, Vomiting | 3 | Negative | 8 | ||
Preoperative diagnosis (n=25) | Adjuvant chemotherapy (n=20) | ||||
Bile duct cancer | 20 | Yes | 5 | ||
Neuroendocrine carcinoma | 3 | No | 15 | ||
Not mentioned | 2 | Neoadjuvant chemotherapy | 3 | ||
Location (n=25) | Bd | 16 | Recurrent organ (n=15) | ||
Bp | 9 | Liver | 11 | ||
Size (n=25) | median 25mm (range 3-62) | Lymph node | 4 | ||
Ki-67 index (n=19) | Lung | 3 | |||
median 71.4% (range 20-90) | Local / Bone | 2 | |||