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Table 2 Summary of 25 reported cases of primary extrahepatic bile duct neuroendocrine carcinoma

From: Rapidly progressed neuroendocrine carcinoma in the extrahepatic bile duct: a case report and review of the literature

Sex (n=25) Male 20 Operation (n =25)
  Female 5   Pancreatoduodenectomy 12
Age (n=25) median 70 years (range 28-84)   Bile duct resection 9
Symptom Jaundice 22   With hepatectomy 4
  Abdominal pain 6 Lymph node metastasis (n=20)
  Weight loss 3   Positive 12
  Nausea, Vomiting 3   Negative 8
Preoperative diagnosis (n=25) Adjuvant chemotherapy (n=20)
  Bile duct cancer 20   Yes 5
  Neuroendocrine carcinoma 3   No 15
  Not mentioned 2 Neoadjuvant chemotherapy 3
Location (n=25) Bd 16 Recurrent organ (n=15)
  Bp 9   Liver 11
Size (n=25) median 25mm (range 3-62)   Lymph node 4
Ki-67 index (n=19)   Lung 3
  median 71.4% (range 20-90)   Local / Bone 2