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Table 1 Previously reported cases of cholesterol granuloma in the mediastinum

From: Multifocal cholesterol granulomas of the anterior mediastinum

Authors Age/sex Background Site Size (cm)/mono or multifocal Radiological findings Surgical procedure
Luckraz et al. [1] 74/M Aortic stenosis Anterior 0.7 × 2.0 × 2.7/mono No data Extirpation through median sternotomy
Fujimoto et al. [2] 62/M Myocardial infarction, thrombosis in the left atrium, dyslipidemia, on warfarin Anterior 2.0 × 1.8/mono CT: slight contrast enhancement, spotty calcification within the tumor; PET: an increased uptake; MRI: low signal intensity on both T1- and T2-weighted images Extirpation through median sternotomy
Shindo et al. [5] 55/M None Posterior 4.5 × 7.0/mono CT: non-contrast enhancement, MRI: high signal intensity on both T1- and T2-weighted images Extirpation through VATS
Ezzat et al. [6] 75/M Angina, hypertension, peripheral vascular disease, COPD, dyslipidemia, smoker, trauma Anterior 2.0 × 3.0 × 3.0/mono No data Extirpation through median sternotomy
Krishman et al. [7] 65/M Third degree heart block, pericarditis, hypertension, coronary artery stenosis Anterior 1.0 × 1.9 × 2.0/mono No data Extirpation through median sternotomy
Ghigna et al. [8] 53/M None Anterior 2.0 × 3.0 × 5.0/mono No data Thymectomy through median sternotomy
Ghigna et al. [8] 25/M Car racer Anterior 1.2 × 2.5 × 4.0/mono No data Thymectomy through median sternotomy
Kawai et al. [9] 68/F Chronic thyroiditis Anterior 1.0 × 2.0/mono CT: non-contrast enhancement, scattered nodules within the tumor; PET: an increased uptake; MRI: low signal intensity on both T1- and T2-weighted images Extended thymectomy through median sternotomy
Drury et al. [10] 74/M COPD, atrial fibrillation Anterior 3.2/mono CT: focal calcification, PET: an increased uptake Thymectomy through VATS
Kobayashi et al. [11] 64/F Diabetes mellitus Anterior 2.0 × 1.7/mono CT: non-contrast enhancement, MRI: low signal intensity on both T1- and T2-weighted images Thymectomy through VATS
Nagata et al. [12] 56/F Dyslipidemia Anterior 2.0 × 2.0 × 1.0, 1.3 × 1.3 × 1.2/multi CT: non-contrast enhancement, PET: an increased uptake Extended thymectomy through median sternotomy
Our case (2020) 71/F Dyslipidemia, hypertension, aortic aneurysm, coronary artery stenosis, old cerebrovascular infarction Anterior 4.2 × 2.6, 3.2 × 3.0; 2.6 × 2.6, 2.3 × 2.3/multi CT: slight contrast enhancement, spotty calcification within the tumor Total thymectomy through median sternotomy