Table 1 Clinical literature review of parathyroid carcinoma in children under 16
From: Parathyroid carcinoma in a 13-year-old girl with a long-term survival
Year | Sex | Age | Ca, mg/dL | i-PTH, pg/mL | Symptoms | Family history | Palpable neck mass | Operation | Outcome |
|---|---|---|---|---|---|---|---|---|---|
1973 [2] | – | 13 | – | – | – | – | – | – | – |
1984 [3] | M | 15 | 112.6 | – | Pancreatitis | – | No | PTx | – |
1984 [1] This case | F | 13 | 15.9 | – | Bone pain | No | – | PTx | Lung meta at 9, 20 yrs Local rec at 42 yrs |
1993 [4] | M | 14 | 13.2 | 353 | Bone pain | Yes | Yes | En bloc resection | No rec after 2 yrs |
1999 [5] | M | 15 | 20.7 | 154 | Fatigue, nausea, weight loss | – | Yes | En bloc resection | No rec after 1 yr |
2002 [6] | F | 8 | 14.3 | 82 | Renal stone | Yes | Yes | PTx | No rec after 16 ms |
2009 [7] | M | 10 | 15.5 | – | Anorexia, fatigue, knee pain | Yes | No | Mediastinal PTx, thymectomy | No rec after 18 ms |
2011 [8] | F | 14 | 14.3 | 2792 | Arthralgia | No | – | HTx | No rec after 18 ms |
2012 [9] | F | 13 | 12.0 | 8363 | None | No | Yes | En bloc resection | Lung meta after 6 ms |
2012 [10] | M | 11 | – | 1630 | Bowing legs with pain | – | – | PTx→HTx | – |
2015 [11] | F | 10 | 12.2 | 2217 | Abdominal pain, joint deformity | – | – | – | – |
2016 [12] | F | 8 | 12.5 | 453 | – | No | – | PTx | Local rec at 5 yrs Lung meta at 5 yrs |
2016 [13] | M | 14 | 17.1 | 1164 | Hip pain | No | Yes | En bloc resection | No rec after 1 yr |
2016 [14] | F | 14 | 13.4 | 1013 | Leg pain | No | Yes | En bloc resection | No rec after 6 ms |
2019 [15] | F | 15 | 15.8 | 1170 | Fever, fatigue | No | Yes | En bloc resection | No rec after 2 yrs |
2020 [16] | M | 13 | 15.4 | 980 | Polyuria, polydipsia, leg pain | No | – | En bloc resection | No rec after 1.5 yrs |
2020 [17] | M | 10 | 14.3 | 1075 | Back pain | – | – | PTx | – |