Fig. 3

Histopathology of the malignant adenomyoepithelioma. a Gross specimen of malignant AME. Red markers show malignant lesions, and blue markers show ductal lesions. The size of tumor was 110 × 105 × 55 mm. b Histopathology of the malignant AME. The tumor was consisted of both epithelial cells, which was positive for CAM 5.2, and myoepithelial cells, which was positive for α-smooth muscle actin (SMA). Ki-67 labeling index (Ki-67) was 44%. The myoepithelial cells were strongly positive for P53. × 200