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Surgical Case Reports
Fig. 1 | Surgical Case Reports

Fig. 1

From: Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue?

Fig. 1

Case of a 74-year-old male. a Well differentiated pancreatic ductal adenocarcinoma near dilated, pancreatic gland in the bowel wall exhibiting architectural and cytologic atypia [hematoxylin and eosin (H&E) stain; 4×]. b Tumor cells are negative for CDX2 in neoplastic glands, compared to normally immunoreactive colonic mucosa (10×). c Complementary CK7 positivity of neoplastic glands and negativity of the non-neoplastic colonic mucosa (10×). d Atypical pancreatic glands close to normal pancreatic glands (H&E stain; 4×). Case of a 78-year-old female. e Well differentiated pancreatic ductal adenocarcinoma near to the pancreatic gland in the bowel wall (H&E stain; 4×). f Immunohistochemistry (IHC) shows negativity for CDX2 in neoplastic glands associated to positivity in the normal colonic mucosa (10×). g IHC shows positivity for CK7 in neoplastic glands associated to negativity in the normal colonic mucosa (10×). h Dysplastic pancreatic glands (H&E stain; 4×). Scale bars 100 μm

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