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Table 1 A search for Japanese literature showed 46 reported cases of gallbladder metastasis from RCC

From: Gallbladder metastasis of renal cell carcinoma presenting as a hypervascular polypoid lesion: case report of two cases with immunohistochemical analysis

ParameterNo. of patients (%)Median (range)
SexMale, 37 (81) 
Female, 9 (19)
Age 64.8 years (43–80)
Symptom+, 10 (22) 
−, 36 (78)
TimingSyn, 12 (26) 
Meta, 34 (74)6 years (0.2–27)a
StagebI, 11 (23.9) 
II, 5 (10.9) 
III, 3 (6.5) 
IV, 13 (28.3) 
Not reported, 14 (30.4) 
Operation procedureEC, 8 (17.4) 
OC, 25 (54.3)
LC, 13 (28.3)
Maximum diameter 18 mm (5–75)
Macroscopic findingsPeduncuated, 37 (80) 
Mass, 9 (20)
Metastasis to other organs+, 28 (61) 
−, 18 (39)
OutcomeAlive, 31 (67)10 months (1–96)c
Dead, 6 (13)
Not reported, 9 (20)
  1. Syn synchronous, Meta metachronous, EC extended cholecystectomy, OC open cholecystectomy, LC laparoscopic cholecystectomy
  2. aDuration to detect metachronous gallbladder metastasis from nephrectomy
  3. bPost-nephrectomy staging
  4. cFollow-up period