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Surgical Case Reports
Fig. 2 | Surgical Case Reports

Fig. 2

From: Metachronous rectal metastasis from pulmonary adenocarcinoma after 11 years of chemo-, immuno-, and radiotherapy for recurrent lesions: a case report

Fig. 2

Histological and immunohistochemical (IHC) studies. Macroscopically, a the resected rectum specimen appeared to be a 30 × 25 mm tumor. A b loupe image of the tumor with hematoxylin and eosin (H&E)-stained section showed that the tumor was located mainly between the submucosal and subserosal layers. Histologic examination of this c and other H&E-stained sections showed that the tumor consisted of dysplastic cells with fused glandular structures and that it contained some mucinous components. Upon IHC staining, the tumor was positive for d anti-cytokeratin (CK) 7 and e thyroid transcription factor-1 (TTF-1), but negative for f CK20, g special AT-rich sequence-binding protein 2 (SATB2), and h anti-caudal type homeobox 2 (CDX2). IHC sections were stained with diaminobenzidine (brown) and counterstained with hematoxylin. Scale bars, 1 mm (b) and 100 μm (c–h). Original × 40 magnification (c–h)

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