Table 1 Previous reports of thymic LELC with a summary of clinical manifestations
From: Total thymectomy for thymic lymphoepithelioma-like carcinoma—report of two cases
Reference | Age | Sex | Symptom | Clinical Masaoka stage | Treatmemt | Recurrence | Outcome | ||
|---|---|---|---|---|---|---|---|---|---|
1 | Taylor et al. [10] | 1988 | 43 | F | Chest pain, cough | IVb | RT + CTx | – | 28 m D |
2 | 28 | M | Chest pain | IVb | RT + CTx | – | 36 m D | ||
3 | Dimery et al. [11] | 1988 | 30 | F | Short of breath | IVb | RT + CTx | – | 24 m A* |
4 | Hartmann et al. [12] | 1990 | 38 | F | Dyspnoea | IVb | RT + CTx | – | 5 m D |
5 | 68 | M | Dyspnoea, chest pain, weight loss | – | S + ART | Lung | 3 m D | ||
6 | 46 | M | Short of breath | IVb | RT | – | 9 m D | ||
7 | Kuo et al. [13] | 1990 | 19 | M | Chest pain, cough | IVa | S + ACRT | Local recurrence, LN, bone | 39 m D |
8 | 41 | M | Chest pain | IVb | S + ACRT | Lung, bone | 19 m D | ||
9 | Fujii et al. [14] | 1993 | 13 | F | None | IVb | S + ACRT | Lung, dissemination | 22 m D |
10 | Niehues et al. [15] | 1996 | 14 | M | Weight loss | – | S + ACRT | Local recurrence, LN | 12y A* |
11 | Hsu et al. [16] | 1998 | 65 | F | Chest pain | – | S + RT | None | 6 m A |
12 | Takahashi et al. [17] | 2000 | 66 | F | None | III | S | Lung, dissemination | 35 m D |
13 | Nicolato et al. [18] | 2001 | 55 | M | Chest pain, cough | IV | CTx | – | – |
14 | Yaris et al. [19] | 2006 | 16 | F | Cheast pain, dyspnoea | IVb | RT + CTx | – | 15 m D |
15 | Tacyildiz et al. [20] | 2007 | 10 | M | Chest pain | III | CTx + S + ACRT | None | 12 m A |
16 | Kilis-Pstrusinska et al. [21] | 2008 | 16 | M | Cough | – | CTx | – | 11 m D |
17 | Sekihara et al. [22] | 2014 | 14 | M | Chest pain | IVb | CTx | – | 10 m D |
18 | Shima et al. [23] | 2016 | 22 | M | Chest pain, dyspnoea | IVa | RT + CTx | – | – |
19 | Suster et al. [24] | 2018 | 55 | M | None | II | S | None | 16y A |
20 | 57 | F | Fatigue | II | S | None | 16y A | ||
21 | 55 | M | None | I | RT | – | 8y A* | ||
22 | 60 | M | None | II | No treatment | – | 7y A | ||
23 | 20 | M | Cough, short of breath | IV | RT + CTx | – | 12 m A* | ||
24 | 67 | F | Chest pain, cough | III | No treatment | – | 1 m D | ||
25 | Pan et al. [25] | 2019 | 7 | M | Short of breath | IVb | S + ACRT | – | – |
26 | Our cases | 65 | F | Chest pain | II | S | None | 10 m A | |
27 | 81 | F | None | II | S | LN | 7 m D | ||