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Fig. 4 | Surgical Case Reports

Fig. 4

From: Fairly rare small-diameter hepatocellular carcinoma with right adrenal gland metastasis having an inferior vena cava tumor thrombus: a case report

Fig. 4

Immunohistochemical findings of HCC and adrenal tumor. a–e HCC and f–j adrenal tumor. a, f HCC (a) and adrenal (f) tumor are both diffusely positive for Glypican-3 (× 200). b, g Alpha-fetoprotein is partially expressed in the HCC (b) and only focally in the adrenal tumor (g, arrowhead) (× 200). c, d, h, i Vimentin was negative for HCC (c) and adrenal (h) tumor, and Melan-A (d) was also negative for HCC. In the adrenal tumor, slight positivity of Melan-A was observed (i), but the intensity of staining was clearly weak compared with that in the normal adrenal glands. (c, d × 200, h, i × 100; Ad, adrenal glands; Tu, tumor) e, j Positivity of CD133 is detected in both HCC (e) and adrenal (j) tumor (× 200)

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