Primary amelanotic malignant melanoma of the esophagus: a case report

Koga, Naomichi; Kubo, Nobuhide; Saeki, Hiroshi; Sasaki, Shun; Jogo, Tomoko; Hirose, Kosuke; Nakashima, Yuichiro; Oki, Eiji; Koga, Yutaka; Oda, Yoshinao; Oiwa, Hisao; Oiwa, Toshio; Maehara, Yoshihiko

doi:10.1186/s40792-019-0564-2

Surgical Case Reports

Table 1 Search results for case reports of amelanotic malignant melanoma of the esophagus between 1996 and 2018 [2, 7,8,9,10,11,12,13,14,15,16,17,18]

From: Primary amelanotic malignant melanoma of the esophagus: a case report

Reference	Age/sex Tumor size	Endoscopic findings	Location	TNM stage	Preoperative diagnosis	Treatment	Prognosis
Lee et al. [15]	47/M 3 cm	Polypoid tumor	Lower esophagus	n.a.	n.a.	Surgery	Died 4 months after surgery
Lee et al. [15]	39/F 1.5 cm	Polypoid and ulcerated tumor	Lower esophagus	n.a.	Poorly-differentiated carcinoma	Surgery	No recurrent 4 months from surgery
Suzuki et al. [8]	58/M 6.5 cm	Ulcerated tumor	Middle esophagus	T3N1M0, III	Squamous cell carcinoma	Surgery, CT, IT and ET	Alive 53 months after surgery(recurrence at 11 months)
Heidemann et al. [7]	75/M 8 cm	Ulcerated tumor	Middle and distal esophagus	n.a.	n.a.	Surgery	Recurrent at 7 months
Stringa et al. [10]	59/M 7.5 cm	Polypoid and ulcerated tumor	Lower third of the esophagus	n.a.	n.a.	Surgery	Disseminated 14 months after surgery
De Smione et al. [9]	58/F 3 cm	Polypoid tumor	Middle esophagus	pT1N0M0, IA	Squamous cell carcinoma	Surgery	Died 16 months after surgery
Wang et al. [16]	n.a. n.a.	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.
Kranzfelder et al. [11]	57/F 7 cm	Ulcerated tumor	Distal esophagus	n.a.	PMME	Surgery and RT	Died 4 months after sugery
Terada et al. [12]	87/F n.a.	Ulcerated tumor	Distal esophagus	n.a.	n.a.	CT and RT	Died 12 months after first presentation
Terada et al. [12]	56/M n.a.	Polypoid tumor	Middle esophagus	n.a.	n.a.	CT and RT	Died 7 months after first presentation
Carr-Locke et al. [18]	66/F 3.5 cm	Polypoid and ulcerated tumor	distal esophagus	n.a.	n.a.	Surgery	Alive 2 months after surgery
Lohmann et al. [13]	63/M 3.6 cm	Sessile tumor	Middle esophagus	n.a.	n.a.	Surgery and CT	Died 12 months after diagnosis
Lohmann et al. [13]	67/F 2.2 cm	Polypoid and ulcerated tumor	Middle esophagus	n.a.	n.a.	Surgery	Alive 60 months after surgery
Lohmann et al. [13]	72/M n.a.	Polypoid tumor	Middle esophagus	n.a.	n.a.	Laser ablation	Died 13 months after diagnosis
Lohmann et al. [13]	70/F 10 cm	Sessile and ulcerated tumor	Distal esophagus	n.a.	n.a.	Surgery	Died 2 months after diagnosis
Lohmann et al. [13]	58/F 11 cm	Polypoid and ulcerated tumor	Distal esophagus	n.a.	n.a.	Surgery	Died 4 months after diagnosis
Ramaswamy et al. [17]	24/F 4.3 cm	Polypoid tumor	Cervical esophagus	n.a.	n.a.	Surgery and CT	Died 8 months after first presentation
Hirayama et al. [14]	77/F 2 cm	Polypoid tumor	Middle esophagus	n.a.	PMME	Surgery	No recurence 3 year after surgery
Kobayashi et al. [2]	68/M 2 cm	Polypoid tumor	Middle esophagus	T1bN0M0, IA	Malignant tumor	Surgery	No recurrence 1.5 year after surgery
Current case	86/F 3 cm	Polypoid tumor	Distal esophagus	T2N0M0, II	Squamous cell carcinoma	Surgery	No recurrent finding 12 months from surgery

This article is included in the review of Bisceglia et al. [13]. M male, F female, n.a. not available, CT chemotherapy, RT radiation therapy, ET endocrine therapy, IT immunotherapy

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