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Fig. 4 | Surgical Case Reports

Fig. 4

From: Resected thymic large cell neuroendocrine carcinoma: report of a case

Fig. 4

Histopathologic findings. Atypical cell nests with large nuclei are seen with lung invasion (a). Tumor cells form nests showing a palisading or organoid pattern (b). Cells with bizarre or multiple nuclei are also seen (c). Immunohistochemistry shows positive staining for CD56 (d), chromogranin A (e), synaptophysin (f), and TTF-1 and negative staining for CD5 and p40. The pathologic diagnosis is large cell neuroendocrine carcinoma of the thymus

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