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Surgical Case Reports
Fig. 4 | Surgical Case Reports

Fig. 4

From: Rectal cancer developing from an anastomotic site 18 years after resection due to intussusception caused by Peutz-Jeghers polyposis in a 31-year-old man: a case report

Fig. 4

Scheme of rectal cancer developing from the anastomotic site in the present case. a Healing state of anastomotic leakage when the patient was 12 years old. The healing process of abscess formation by anastomotic leakage may lead to heterotopic ossification and repair of rectal mucosa, inducing the incorporation of rectal mucosa into the bone tissue (M, rectal mucosa; PM, proper smooth muscle layer; F, fibrosis of anastomotic site; arrowheads indicate rectal mucosa incorporated into the bone tissue). b Development of cancer at the anastomotic site 18 years later. Cancer may arise from the rectal mucosa in the cavity or the stromal tissue, subsequently invade into adjacent tissues including bone tissue, and protrude into the rectal lumen through the orifice of the cavity

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