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Fig. 3 | Surgical Case Reports

Fig. 3

From: Rectal cancer developing from an anastomotic site 18 years after resection due to intussusception caused by Peutz-Jeghers polyposis in a 31-year-old man: a case report

Fig. 3

Macroscopic and microscopic photographs of the resected rectum. a The surface of the resected rectum shows mucosal defect (white arrow) and a submucosal tumor on the anastomotic line. b The cut surfaces of the rectum demonstrate a submucosal tumor with bone lesion underneath the mucosal defect (white arrowheads). c Histologically, the tumor with bone lesion (*) occupies the muscle layer and submucosal area (whole-mount image; hematoxylin-eosin [HE] stain). d Part of the surface of the tumor is covered by granulation tissue, indicating erosion (× 20; HE stain). e Image showing adenocarcinoma invading into the bone lesion (× 5; HE stain). f Normal mucosa in the submucosal fibrosis (black arrow) and the bone lesion in the proper muscle layer (black square) at the anastomotic site (× 2; Elastica van Gieson stain). Inset: a high-power view of the area within the black square (HE stain)

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