Fig. 3From: A neuroendocrine carcinoma with a well-differentiated adenocarcinoma component arising in Barrett’s esophagus: a case report and literature reviewHistopathological findings. a Hematoxylin-eosin staining shows that the tumor arose in Barrett’s epithelium (× 40). b Magnification of the part indicated by the square in (a) (× 100). The tumor shows two components (black and white arrows). The black arrow indicates a well-differentiated adenocarcinoma, whereas the white arrow indicates a neuroendocrine carcinoma. c Immunohistochemical staining for chromogranin A is positive (× 200). d Immunohistochemical staining for synaptophysin is positive (× 200)Back to article page