Table 1 Literature review of clinical and genetic characteristics of 21 medullary carcinomas of the pancreas
Case | Authors (reference no.) | Age | Sex | *MSI | Family history | KRAS mutation | Status (months) |
|---|---|---|---|---|---|---|---|
1 | Goggins et al. [1] | 71 | M | + | + | Wild | Alive (67) |
2 | 84 | F | + | + | Wild | DOD (4) | |
3 | 72 | M | + | + | Wild | Alive (24) | |
4 | 85 | M | − | + | G12D | DOD (40) | |
5 | 65 | M | − | + | G12R | DOD (9) | |
6 | Wilentz et al. [2] | 72 | M | − | + | G12R | DOD (0) |
7 | 74 | F | − | Unknown | Wild | DOD (8) | |
8 | 79 | M | − | + | G12D | DOD (5) | |
9 | 53 | F | − | + | Wild | DOD (45) | |
10 | 44 | M | − | Unknown | Wild | DOD (11) | |
11 | 49 | M | − | Unknown | Wild | DOD (15) | |
12 | 74 | M | − | + | Wild | DOD (12) | |
13 | 74 | F | − | Unknown | Wild | DOD (12) | |
14 | 34 | M | + | + | Wild | Alive (13) | |
15 | 33 | M | − | − | Wild | Alive (126) | |
16 | 67 | F | − | + | G12F | DOD (15) | |
17 | 67 | M | − | + | G12D | DOD (4) | |
18 | 66 | F | − | + | Wild | DOD (7) | |
19 | Banville et al. [3] | 63 | M | + | + | Not done | Unknown |
20 | Cumplido Buron and Toral Pena [4] | 59 | M | Not done | Unknown | Wild | DOD (5) |
21 | The present case | 73 | F | − (IHC) | − | G12 V | Alive (29) |